By Watson Pharmaceuticals

What is this medication for?

Diethylpropion belongs to the family of medications known as anorexiants (appetite suppressants). It is used in addition to dietary measures for the short-term (a few weeks) management of obesity for people who have not responded to an appropriate weight-reducing diet alone. It works by causing one to feel less hungry.

It is recommended only for people with an initial body mass index (BMI) of 30 kg/m2 or greater. Body mass index is a number calculated with consideration to weight and height. Ask your health professional about your BMI.

You should begin to lose weight within the first week of taking diethylpropion at an approximate rate of one pound per week. However, every person is different and this rate of weight loss may not be the same for you.

Your doctor may have suggested this medication for conditions other than those listed here. As well, some forms of this medication may not be used for all of the conditions discussed here. If you are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

What form(s) does this medication come in?

Tenuate® is available as:

  • tablet
    • 25 mg
Some medications may have other generic brands available. Always ask your doctor or pharmacist about the safety of switching between brands of the same medication.

How should I use this medication?

The usual adult dose of diethylpropion is one 25 mg tablet taken 3 times daily, one hour before meals and one tablet in mid-evening, if desired, to overcome night hunger.

The usual adult dose of diethylpropion controlled release is one 75 mg tablet taken once daily in mid-morning, swallowed whole. This medication should not be used for more than 4 weeks if satisfactory weight loss has not occurred (as determined by your doctor).

This medication may be taken with or without food. The controlled release tablet must be swallowed whole and not crushed or split.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Who should NOT take this medication?

Do not take this medication if you:

  • are allergic to diethylpropion, sympathomimetic amines (e.g., amphetamines, methylphenidate) or any ingredients of the medication
  • are taking MAO inhibitors (e.g., phenelzine or tranylcypromine), or have taken them within the past 14 days
  • are subject to agitated states
  • are taking other appetite suppressants
  • have advanced arteriosclerosis
  • have a condition known as pulmonary artery hypertension
  • have glaucoma
  • have heart disease
  • have a heart murmur or valvular heart disease
  • have high blood pressure
  • have a history of drug abuse
  • have a history of or family history of mental illness
  • have kidney disease
  • have an overactive thyroid
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The contents of this health site are for informational purposes only. Always seek the advice of your physician or other qualified healthcare provider regarding any questions you may have about a medical condition.

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