Epiduo

adapalene - benzoyl peroxide

By Galderma

What side effects are possible with this medication?

A side effect is an unwanted response to a medication when it is taken in normal doses. A side effect may be mild or severe, temporary or permanent, but does not occur in everyone. The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away over time. If you develop any of these side effects (or any other side effects not listed here) or they change in intensity, speak to your doctor or pharmacist for advice on managing them and on the risks and benefits of the medication.

  • dry skin
  • increased sensitivity to sun
  • peeling skin
  • redness
  • skin irritation
  • stinging or burning skin
Click here to learn about serious side effects that can potentially occur with any medication. These examples are provided for information purposes only and are not meant to be exhaustive. Always consult your doctor for sound medical advice specific to your particular medication and treatment.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online or by phone at 1-800-332-1088.

Are there any other precautions or warnings for this medication?

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Area of use: Adapalene - benzoyl peroxide is for external use only. Avoid applying to the areas near the eyes, lips, angles of the nose, mucous membranes, or to open wounds.

Bleaching: This medication may bleach hair and colored fabrics.

Other products: Avoid using other topical products that can irritate the skin, such as harsh soaps and cleansers, cosmetics and soaps that have strong-drying effects, and products with high concentrations of alcohol or astringents. Also avoid using waxing as a hair removal method while using this medication.

Sun exposure: Adapalene - benzoyl peroxide may increase the sensitivity of the skin to sun. Avoid exposure to excessive sunlight (outdoors, sunlamps, and tanning beds). If you cannot avoid exposure to the sunlight, apply sunscreen and wear protective clothing (such as long sleeves and a hat) to reduce the risk of severe sunburn.

Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.

Breast-feeding: It is not known if adapalene or benzoyl peroxide passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of this medication have not been established for children under 12 years of age.

What other drugs could interact with this medication?

There may be an interaction between adapalene - benzoyl peroxide and any of the following:

  • any topical product that causes drying or peeling of the skin
  • topical astringents
  • harsh soaps
  • resorcinol
  • salicylic acid
  • sulfur

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

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The contents of this health site are for informational purposes only. Always seek the advice of your physician or other qualified healthcare provider regarding any questions you may have about a medical condition.

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