Adderall

mixed salts amphetamine

By Shire

What side effects are possible with this medication?

A side effect is an unwanted response to a medication when it is taken in normal doses. A side effect may be mild or severe, temporary or permanent, but does not occur in everyone.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away over time. If you develop any of these side effects (or any other side effects not listed here) or they change in intensity, speak to your doctor or pharmacist for advice on managing them and on the risks and benefits of the medication.

  • anxiety, agitation, nervousness, or mood changes
  • diarrhea
  • dizziness or lightheadedness
  • dry mouth
  • fatigue
  • fever
  • headache
  • increased heart rate
  • infections
  • loss of appetite or weight loss
  • nausea, heartburn, stomach ache, or vomiting
  • trouble sleeping
  • uncontrolled movements
  • urinary tract infection
  • weakness
Click here to learn about serious side effects that can potentially occur with any medication. These examples are provided for information purposes only and are not meant to be exhaustive. Always consult your doctor for sound medical advice specific to your particular medication and treatment.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online or by phone at 1-800-332-1088.

Are there any other precautions or warnings for this medication?

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Blood pressure: This medication can increase blood pressure. Be careful in your use of this medication if you have high blood pressure, heart failure, or overactive thyroid, or have recently had a heart attack. Your blood pressure should be monitored at appropriate intervals.

Drug holidays: Talk to your doctor about whether a "drug holiday" (not taking this medication during school or work holidays) might be appropriate for you or your child.

Exercise: If you participate in strenuous exercise or activities, consult your doctor before taking mixed salts amphetamine.

Heart problems: This medication can increase heart rate and blood pressure. It may also increase the risk of sudden death for people with heart problems. If you have heart problems, including an irregular heartbeat, or a family history of sudden death related to heart disease, your doctor should carefully evaluate your condition before you start this medication, and should closely monitor your condition if you take the medication. This medication should generally not be used by people with known structural heart abnormalities (such as abnormal size, missing or poorly functioning heart valves, or problems with blood vessels connected to the heart).

Long-term use: If you will be using this medication for a long period of time, you will need regular heart check-ups by your doctor.

Potential for abuse: Mixed salts amphetamine has a high potential for abuse. Using this medication for a prolonged period of time may lead to drug dependence. Misuse of this medication could lead to serious heart problems and sudden death.

Psychosis: This medication may increase abnormal thoughts and behaviors in people suffering from psychotic conditions, or cause these symptoms to emerge. If you notice the appearance of new or worsening symptoms, including hallucinations, delusional thinking, or aggressive or hostile behavior, talk to your doctor as soon as possible.

Reduced alertness: Use caution when driving, operating machinery, or performing other hazardous activities.

Seizures: Rarely, stimulant medications (such as mixed salts amphetamine) can cause seizures for people who are at risk of seizures (such as those with a family or personal history of seizures). Speak to your doctor to see if you may be at risk.

Stopping the medication: Check with your doctor before stopping this medication.

Suppression of growth: It is not known whether mixed salts amphetamine causes growth suppression (i.e., less growth in height or weight than usual). However, this has been reported for children who use stimulants such as this medication over long periods of time. Children who need long-term treatment should be carefully monitored for growth. Their doctor may also recommend a "drug holiday," where the medication is not given on weekends or during school holidays.

Tics: If you have motor tics (a condition that causes a person to make involuntary movements) or phonic tics (a condition that causes a person to make involuntary sounds), Tourette's syndrome, or a family history of Tourette's syndrome, discuss with your doctor how this medication may affect your medical condition, how your medical condition or medications may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Visual changes: This medication may affect your vision. If you notice any changes in your vision such as blurring, talk to your doctor as soon as possible.

Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately to talk about the benefits and risks of using this medication.

Breast-feeding: This medication passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should stop breast-feeding or stop taking this medication.

Children: The safety and effectiveness of mixed salts amphetamine have not been established for children less than 3 years of age.

What other drugs could interact with this medication?

There may be an interaction between mixed salts amphetamine and any of the following:

  • acidifying agents (e.g., guanethidine, reserpine, ammonium chloride)
  • adrenergic blockers (heart medication, e.g., metoprolol)
  • alcohol
  • alkalinizing agents (e.g., sodium bicarbonate, acetazolamide)
  • antihistamines (allergy medication, e.g., chlorpheniramine)
  • antihypertensives (blood pressure medication, e.g., hydrochlorothiazide)
  • chlorpromazine
  • ethosuximide
  • haloperidol
  • lithium
  • meperidine
  • methenamine
  • monoamine oxidase inhibitors (MAOs; e.g., phenelzine, tranylcypromine)
  • other medications for ADHD
  • phenobarbital
  • phenytoin
  • propoxyphene
  • sympathomimetics (e.g., norepinephrine)
  • tricyclic antidepressants (e.g., amitriptyline, desipramine)
  • veratrum alkaloids

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

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The contents of this health site are for informational purposes only. Always seek the advice of your physician or other qualified healthcare provider regarding any questions you may have about a medical condition.

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