What side effects are possible with this medication?
A side effect is an unwanted response to a medication when it is taken in normal doses. A side effect may be mild or severe, temporary or permanent, but does not occur in everyone. Not everyone will experience side effects, and which side effects a person experiences cannot be anticipated.
The following side effects have been reported by at least 1% of people taking this medication. If you develop any of these side effects (or any other side effects not listed here) or they change in intensity, speak to your doctor or pharmacist for advice on managing them and on the risks and benefits of the medication.
- blurred vision
- burning, stinging, or irritated eyes upon instillation of eye drops
- crusting on eyelid or corner of eye
- discoloration of white part of eye
- drowsiness or tiredness
- dry eyes
- dryness of mouth
- eye tearing
- itching of eye
- redness of eye or inner lining of eyelid
- sensitivity to light (wearing sunglasses may help)
to learn about serious side effects that can potentially occur with any medication. These examples are provided for information purposes only and are not meant to be exhaustive. Always consult your doctor for sound medical advice specific to your particular medication and treatment.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online or by phone at 1-800-332-1088.
Are there any other precautions or warnings for this medication?
Be sure to inform your doctor of all your medical conditions before you begin taking a medication. Some conditions can affect how you should take this medication.
Depression: People with clinical depression should use caution when using this medication.
Drowsiness/reduced alertness: Brimonidine may impair the mental and physical abilities required for driving a car or operating heavy machinery.
Orthostatic hypotension: Orthostatic hypotension, also known as postural hypotension, is a drop in blood pressure upon arising. People who experience this should use caution when using this medication.
Raynaud's disease: Raynaud's disease is a disorder of the small blood vessels that feed the skin. People with this condition should use caution when using this medication.
Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: It is not known if brimonidine eye drops passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of this medication have not been established for children under the age of 2 years old.
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What other drugs could interact with this medication?
An interaction between medications does not always mean that you must stop taking one of them. The following medications may affect the way brimonidine works, be affected by brimonidine, or increase the risk of side effects:
- blood pressure-lowering medications (e.g., metoprolol, enalapril, hydrochlorothiazide)
- MAOIs (e.g., phenelzine, tranylcypromine, selegiline)
- other drugs causing sedation (e.g., alcohol, phenobarbital, codeine, and morphine)
- tricyclic antidepressants (e.g., amitriptyline, imipramine)
If you are taking any of these or other medications (including non-prescription, herbal, and supplement products), speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want to change your therapy or may suggest ways of managing any interactions. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your doctor know if you use them. Medications other than those listed above may also interact with this medication.